The name 'Kiyo' originates from the Japanese word 清 (kiyo), which means 'clear, pure, clean.' It can also be derived from other homophonic words in Japanese. The name was particularly popular during the Edo period and remained common until the early 20th century, often spelled in katakana during that time. In Japanese folklore, 'Kiyohime' (清姫) is a notable character from the story of Anchin and Kiyohime, where she transforms into a serpent out of unrequited love for a Buddhist monk.