Santuzza is a diminutive form of the name Santa, which is derived from the Latin word 'sanctus', meaning 'holy' or 'saint'. In the context of the opera 'Cavalleria rusticana', Santuzza is a central character whose story reflects themes of love, betrayal, and honor in a rustic Sicilian setting. The name Santuzza, while diminutive, carries significant emotional weight within the narrative, symbolizing both innocence and tragedy.